P460: Gene- and variant-specific calibration of in silico predictive models results in reclassification of 28% of missense VUS from ClinGen VCEPs

• Shawn Fayer,
• Malvika Tejura,
• Abbye McEwen,
• Lea Starita,
• Douglas Fowler

Affiliations

Shawn Fayer

University of Washington

Malvika Tejura

University of Washington

Abbye McEwen

University of Washington

Lea Starita

University of Washington

Douglas Fowler

University of Washington