Nature Communications (Oct 2021)

Context value updating and multidimensional neuronal encoding in the retrosplenial cortex

  • Weilun Sun,
  • Ilseob Choi,
  • Stoyan Stoyanov,
  • Oleg Senkov,
  • Evgeni Ponimaskin,
  • York Winter,
  • Janelle M. P. Pakan,
  • Alexander Dityatev

DOI
https://doi.org/10.1038/s41467-021-26301-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

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Goal-directed behaviors require the brain to integrate information across many task-related dimensions. Here, the authors use a virtual context discrimination paradigm in mice to demonstrate the capacity for neurons in the retrosplenial cortex to exhibit multidimensional encoding across learning.