ANTIMICROBIAL EVALUATION OF NOVEL SUBSTITUTED PYRIMIDINOPYRAZOLES AND PYRIMIDINOTRIAZOLES

Abstract

Some novel substituted pyramidinopyrazoles and pyrimidinotriazoles have been synthesized by using 6-anisyl-5-cyano-2-hydrazino-3-N-methyl-3, 4-dihydropyrimidine-4-one as the starting material. Structures of these compounds have been established by IR, 1H NMR, Mass and elemental analysis data and have been evaluated for their antimicrobial activity. Significant antimicrobial activity was observed for some members of these series.

Keywords

• Antimicrobial activity
• Pyramidinopyrazoles
• Pyrimidinotriazoles.