P02 ARGININE DEPRIVATION INDUCES ACQUISITION OF A SENESCENT PHENOTYPE AND FAVORS GENOMIC INSTABILITY IN MULTIPLE MYELOMA PLASMACELLS

• A. Romano,
• G. Scandura,
• C. Giallongo,
• E. La Spina,
• S. Giallongo,
• L. Longhitano,
• T. Zuppelli,
• I. Dulcamare,
• N. L. Parrinello,
• F. Polito,
• R. Oteri,
• M. Aguennouz,
• N. Vicario,
• A. M. Amorini,
• V. Del Fabro,
• C. Conticello,
• G. Li Volti,
• G. A. Palumbo,
• D. Tibullo,
• F. Di Raimondo

Affiliations

A. Romano

1 Department of Clinical and Experimental Medicine - University of Catania, Catania, Italy

G. Scandura

2 Department of Clinical and Expreimental Medicine – University of Catania, Catania, Italy

C. Giallongo

3 Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia” - University of Catania, Catania, Italy

E. La Spina

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

S. Giallongo

1 Department of Clinical and Experimental Medicine - University of Catania, Catania, Italy

L. Longhitano

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

T. Zuppelli

1 Department of Clinical and Experimental Medicine - University of Catania, Catania, Italy

I. Dulcamare

5 Division of Hematology, Azienda Policlinico OVE - University of Catania, Catania, Italy

N. L. Parrinello

5 Division of Hematology, Azienda Policlinico OVE - University of Catania, Catania, Italy

F. Polito

6 Department of Clinical and Experimental Medicine - University of Messina, Messina, Italy

R. Oteri

6 Department of Clinical and Experimental Medicine - University of Messina, Messina, Italy

M. Aguennouz

6 Department of Clinical and Experimental Medicine - University of Messina, Messina, Italy

N. Vicario

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

A. M. Amorini

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

V. Del Fabro

5 Division of Hematology, Azienda Policlinico OVE - University of Catania, Catania, Italy

C. Conticello

5 Division of Hematology, Azienda Policlinico OVE - University of Catania, Catania, Italy

G. Li Volti

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

G. A. Palumbo

1 Department of Clinical and Experimental Medicine - University of Catania, Catania, Italy

D. Tibullo

4 Biometec - Department of Biomedical and Biotechnological Sciences - University of Catania, Catania, Italy

F. Di Raimondo

1 Department of Clinical and Experimental Medicine - University of Catania, Catania, Italy