Tcf12 is required to sustain myogenic genes synergism with MyoD by remodelling the chromatin landscape

Sheng Wang; Yinlong Liao; Haoyuan Zhang; Yunqi Jiang; Zhelun Peng; Ruimin Ren; Xinyun Li; Heng Wang

doi:10.1038/s42003-022-04176-0

Communications Biology (Nov 2022)

Tcf12 is required to sustain myogenic genes synergism with MyoD by remodelling the chromatin landscape

Sheng Wang,
Yinlong Liao,
Haoyuan Zhang,
Yunqi Jiang,
Zhelun Peng,
Ruimin Ren,
Xinyun Li,
Heng Wang

Affiliations

Sheng Wang: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Yinlong Liao: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Haoyuan Zhang: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Yunqi Jiang: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Zhelun Peng: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Ruimin Ren: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Xinyun Li: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University
Heng Wang: Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University

DOI: https://doi.org/10.1038/s42003-022-04176-0
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

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TCF12 contributes to muscle development and regeneration and works with MYOD to govern myogenic genes at gene regulatory regions through chromatin remodelling

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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