P1282: DISEASE-SPECIFIC U1 SPLICEOSOMAL RNA MUTATIONS IN MATURE B-CELL NEOPLASMS

• F. Nadeu,
• S. Shuai,
• G. Clot,
• L. K. Hilton,
• A. Diaz-Navarro,
• S. Martín,
• R. Royo,
• T. Baumann,
• M. Kulis,
• I. López-Oreja,
• M. Cossio,
• J. Lu,
• V. Ljungström,
• E. Young,
• K. Plevova,
• B. A. Knisbacher,
• Z. Lin,
• C. K. Hahn,
• P. Bousquets,
• M. Alcoceba,
• M. González,
• E. Colado,
• M. Aymerich,
• M. J. Terol,
• A. Rivas-Delgado,
• A. Enjuanes,
• S. Ruiz-Gaspà,
• T. Chatzikonstantinou,
• D. Hägerstrand,
• C. Jylhä,
• A. Skaftason,
• L. Mansouri,
• K. Stranska,
• M. Doubek,
• E. J. van Gastel-Mol,
• Z. Davis,
• R. Walewska,
• L. Scarfò,
• L. Trentin,
• A. Visentin,
• S. A. Parikh,
• K. G. Rabe,
• R. Moia,
• M. Armand,
• D. Rossi,
• F. Davi,
• G. Gaidano,
• N. E. Kay,
• T. Shanafelt,
• P. Ghia,
• D. Oscier,
• A. W. Langerak,
• S. Beà,
• A. López-Guillermo,
• D. Neuberg,
• C. J. Wu,
• G. Getz,
• S. Pospisilova,
• K. Stamatopoulos,
• R. Rosenquist,
• W. Huber,
• T. Zenz,
• D. Colomer,
• J. I. Martín-Subero,
• J. Delgado,
• R. D. Morin,
• L. D. Stein,
• X. S. Puente,
• E. Campo

Affiliations

F. Nadeu

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

S. Shuai

3 Department of Human Cell Biology and Genetics, School of Medicine, Southern University of Science and Technology, Shenzhen, China

G. Clot

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

L. K. Hilton

4 Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada

A. Diaz-Navarro

2 Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

S. Martín

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

R. Royo

6 Barcelona Supercomputing Center (BSC)

T. Baumann

7 Hospital Clínic of Barcelona, Barcelona, Spain

M. Kulis

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

I. López-Oreja

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

M. Cossio

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

J. Lu

8 European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

V. Ljungström

9 Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala

E. Young

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

K. Plevova

11 University Hospital Brno & Medical Faculty, Masaryk University

B. A. Knisbacher

13 The Broad Institute of MIT and Harvard

Z. Lin

13 The Broad Institute of MIT and Harvard

C. K. Hahn

13 The Broad Institute of MIT and Harvard

P. Bousquets

5 Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo

M. Alcoceba

2 Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

M. González

2 Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

E. Colado

17 Servicio de Hematología y Hemoterapia, Hospital Universitario Central de Asturias, Oviedo, Sweden

M. Aymerich

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

M. J. Terol

18 Servicio de Hematología, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, Valencia, Spain

A. Rivas-Delgado

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

A. Enjuanes

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

S. Ruiz-Gaspà

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

T. Chatzikonstantinou

19 Institute of Applied Biosciences, Centre for Research and Technology Hellas

D. Hägerstrand

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

C. Jylhä

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

A. Skaftason

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

L. Mansouri

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

K. Stranska

11 University Hospital Brno & Medical Faculty, Masaryk University

M. Doubek

11 University Hospital Brno & Medical Faculty, Masaryk University

E. J. van Gastel-Mol

22 Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands

Z. Davis

23 Department of Molecular Pathology

R. Walewska

24 Department of Haematology, University Hospitals Dorset, Bournemouth, United Kingdom

L. Scarfò

25 Università Vita-Salute San Raffaele, Milan - Strategic Research Program on CLL, Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milan

L. Trentin

26 Department of Medicine, Hematology and Clinical Immunology Section, University of Padua, Padua, Italy

A. Visentin

26 Department of Medicine, Hematology and Clinical Immunology Section, University of Padua, Padua, Italy

S. A. Parikh

27 Division of Hematology

K. G. Rabe

28 Department of Quantitative Health Sciences, Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, United States of America

R. Moia

29 Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy

M. Armand

30 Department of Laboratory Medicine and Pathology, Hospital Pitie-Salpetriere, Sorbonne University, Paris, France

D. Rossi

31 Department of Hematology, Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona, Switzerland

F. Davi

30 Department of Laboratory Medicine and Pathology, Hospital Pitie-Salpetriere, Sorbonne University, Paris, France

G. Gaidano

29 Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy

N. E. Kay

27 Division of Hematology

T. Shanafelt

32 Stanford School of Medicine, Stanford, United States of America

P. Ghia

25 Università Vita-Salute San Raffaele, Milan - Strategic Research Program on CLL, Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milan

D. Oscier

24 Department of Haematology, University Hospitals Dorset, Bournemouth, United Kingdom

A. W. Langerak

22 Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands

S. Beà

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

A. López-Guillermo

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

D. Neuberg

34 Department of Data Science, Dana-Farber Cancer Institute

C. J. Wu

13 The Broad Institute of MIT and Harvard

G. Getz

13 The Broad Institute of MIT and Harvard

S. Pospisilova

11 University Hospital Brno & Medical Faculty, Masaryk University

K. Stamatopoulos

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

R. Rosenquist

10 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

W. Huber

8 European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

T. Zenz

39 Department of Medical Oncology and Hematology, University Hospital and University of Zürich, Zürich, Switzerland

D. Colomer

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

J. I. Martín-Subero

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

J. Delgado

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona

R. D. Morin

4 Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada

L. D. Stein

42 Department of Molecular Genetics, University of Toronto

X. S. Puente

2 Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

E. Campo

1 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona