Diagnostics (Jul 2023)

Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease

  • Christoph Treutlein,
  • Martin Georg Zeilinger,
  • Sven Dittrich,
  • Jan-Peter Roth,
  • Matthias Wetzl,
  • Rafael Heiss,
  • Wolfgang Wuest,
  • Matthias Stefan May,
  • Michael Uder,
  • Oliver Rompel

DOI
https://doi.org/10.3390/diagnostics13142403
Journal volume & issue
Vol. 13, no. 14
p. 2403

Abstract

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(1) Purpose: to compare right ventricular (RV) functional parameters in children with surgically repaired congenital heart disease (CHD) using single/double breath hold (BH) and free-breathing (FB) real-time compressed sensing (CS) cine cardiac magnetic resonance (cMRI) with standard retrospective segmented multi breath hold (RMB) cine cMRI. (2) Methods: Twenty patients with CHD underwent BH and FB, as well as RMB cine cMRI, at 3T to obtain a stack of continuous axial images of the RV. Two radiologists independently performed qualitative analysis of the image quality (rated on a 5-point scale; 1 = non-diagnostic to 5 = excellent) and quantitative analysis of the RV volume measurements. (3) Results: The best image quality was provided by RMB (4.5; range 2–5) compared to BH (3.9; range 3–5; p = 0.04) and FB (3.6; range 3–5; p p p < 0.01) were significantly reduced compared to for RMB (261 ± 68 s). (4) Conclusions: CS-FB and CS-BH real-time cine cMRI in children with CHD provides diagnostic image quality with excellent accuracy for measuring RV function with a significantly reduced scan time compared to RMB.

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