Top-down modulation of olfactory-guided behaviours by the anterior olfactory nucleus pars medialis and ventral hippocampus

Afif J. Aqrabawi; Caleb J. Browne; Zahra Dargaei; Danielle Garand; C. Sahara Khademullah; Melanie A. Woodin; Jun Chul Kim

doi:10.1038/ncomms13721

Nature Communications (Dec 2016)

Top-down modulation of olfactory-guided behaviours by the anterior olfactory nucleus pars medialis and ventral hippocampus

Afif J. Aqrabawi,
Caleb J. Browne,
Zahra Dargaei,
Danielle Garand,
C. Sahara Khademullah,
Melanie A. Woodin,
Jun Chul Kim

Affiliations

Afif J. Aqrabawi: Department of Cell and Systems Biology, University of Toronto
Caleb J. Browne: Department of Psychology, University of Toronto
Zahra Dargaei: Department of Cell and Systems Biology, University of Toronto
Danielle Garand: Department of Cell and Systems Biology, University of Toronto
C. Sahara Khademullah: Department of Cell and Systems Biology, University of Toronto
Melanie A. Woodin: Department of Cell and Systems Biology, University of Toronto
Jun Chul Kim: Department of Cell and Systems Biology, University of Toronto

DOI: https://doi.org/10.1038/ncomms13721
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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The anterior olfactory nucleus pars medialis (mAON) provides cortical feedback to the olfactory bulb, but the behavioural relevance of these projections is unknown. Here, using opto- and chemogenetic approaches, the authors find the mAON bidirectionally modulates olfactory sensitivity and olfaction-dependent behaviours.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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