Effects of cardiac rehabilitation on cognitive function in patients with acute coronary syndrome: A systematic review
Kodai Ishihara,
Kazuhiro P. Izawa,
Masahiro Kitamura,
Yuji Kanejima,
Masato Ogawa,
Ryo Yoshihara,
Tomoyuki Morisawa,
Ikki Shimizu
Affiliations
Kodai Ishihara
Department of Physical Therapy, Faculty of Nursing and Rehabilitation, Konan Women's University, 2-23 Morikitamachi 6-chome, Higashinada-ku, Kobe, 658-0001, Japan; Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan
Kazuhiro P. Izawa
Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan; Corresponding author. Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-Chome, Suma-ku, Kobe, 654-0142, TEL, Japan.
Masahiro Kitamura
Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan; School of Physical Therapy, Faculty of Rehabilitation, Reiwa Health Sciences University, 1-12 Wajirogaoka 2-chome, Higashi-ku, Fukuoka, 811-0213, Japan
Yuji Kanejima
Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan; Department of Rehabilitation, Kobe City Medical Center General Hospital, 1-1 Minatojimaminamicho 2-chome, Chuo-ku, Kobe, 650-0047, Japan
Masato Ogawa
Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan; Department of Rehabilitation, Faculty of Health Sciences, Osaka Health Sciences University, 9-27 Temma 1-chome, Kita-ku, Osaka, 530-0043, Japan
Ryo Yoshihara
Department of Public Health, Graduate School of Health Sciences, Kobe University, 10-2 Tomogaoka 7-chome, Suma-ku, Kobe, 654-0142, Japan; Cardiovascular Stroke Renal Project (CRP), Japan; Department of Rehabilitation, Kobe City Medical Center General Hospital, 1-1 Minatojimaminamicho 2-chome, Chuo-ku, Kobe, 650-0047, Japan
Tomoyuki Morisawa
Department of Physical Therapy, Faculty of Health Sciences, Juntendo University, 2-12 Hongo 3-chome, Bunkyo-ku, Tokyo, 113-0033, Japan
Ikki Shimizu
Department of Diabetes, Sakakibara Heart Institute of Okayama, 5-1 Nakaicho 2-chome, Kita-ku, Okayama, 700-0804, Japan
Background: Construction of an intervention method for the cognitive dysfunction of patients with acute coronary syndrome (ACS) is needed. Exercise-based comprehensive cardiac rehabilitation is a potentially effective approach that can improve cognitive function in ACS patients. This study aimed to investigate the effect of cardiac rehabilitation on cognitive function in ACS patients through a systematic review. Methods: A systematic review was conducted of studies on PubMed, MEDLINE, Web of Science, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) on September 13, 2022, to identify those reporting the effects of cardiac rehabilitation on cognitive function in ACS patients. Data that reported exercise-based comprehensive cardiac rehabilitation and cognitive function (even if not main results and any type of cognitive function assessment was used) were extracted. Results: In total, six studies were included that comprised a total of 1085 ACS patients. Overall positive effects of cardiac rehabilitation on cognitive function in ACS patients were reported across the six studies. All studies included aerobic exercise, resistance exercise, and patient education in cardiac rehabilitation. Meta-analysis could not be undertaken because each dataset used different methods to evaluate cognitive function, and the outcomes were different. Conclusions: This systematic review showed that cardiac rehabilitation could have positive effects on cognitive function in ACS patients. Our results support the efficacy of cardiac rehabilitation for cognitive function in ACS patients. Additional well-designed clinical trials of exercise-based comprehensive cardiac rehabilitation should be conducted to clarify the true effect on cognitive function in ACS patients.
