Nature Communications (Jun 2018)

A multi-modal MRI study of the central response to inflammation in rheumatoid arthritis

  • Andrew Schrepf,
  • Chelsea M. Kaplan,
  • Eric Ichesco,
  • Tony Larkin,
  • Steven E. Harte,
  • Richard E. Harris,
  • Alison D. Murray,
  • Gordon D. Waiter,
  • Daniel J. Clauw,
  • Neil Basu

DOI
https://doi.org/10.1038/s41467-018-04648-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Many diseases, such as rheumatoid arthritis, are characterized by a chronic inflammatory state, but it is not clear whether or how this affects the brain. Here, the authors show that the severity of on-going inflammation predicts altered functional brain connectivity in people with rheumatoid arthritis.