Nature Communications (Apr 2019)
Sequencing of human genomes with nanopore technology
- Rory Bowden,
- Robert W. Davies,
- Andreas Heger,
- Alistair T. Pagnamenta,
- Mariateresa de Cesare,
- Laura E. Oikkonen,
- Duncan Parkes,
- Colin Freeman,
- Fatima Dhalla,
- Smita Y. Patel,
- Niko Popitsch,
- Camilla L. C. Ip,
- Hannah E. Roberts,
- Silvia Salatino,
- Helen Lockstone,
- Gerton Lunter,
- Jenny C. Taylor,
- David Buck,
- Michael A. Simpson,
- Peter Donnelly
Affiliations
- Rory Bowden
- Wellcome Centre for Human Genetics, University of Oxford
- Robert W. Davies
- Genomics plc
- Andreas Heger
- Genomics plc
- Alistair T. Pagnamenta
- Wellcome Centre for Human Genetics, University of Oxford
- Mariateresa de Cesare
- Wellcome Centre for Human Genetics, University of Oxford
- Laura E. Oikkonen
- Wellcome Centre for Human Genetics, University of Oxford
- Duncan Parkes
- Wellcome Centre for Human Genetics, University of Oxford
- Colin Freeman
- Wellcome Centre for Human Genetics, University of Oxford
- Fatima Dhalla
- Department of Clinical Immunology, Oxford University Hospitals
- Smita Y. Patel
- Department of Clinical Immunology, Oxford University Hospitals
- Niko Popitsch
- Wellcome Centre for Human Genetics, University of Oxford
- Camilla L. C. Ip
- Wellcome Centre for Human Genetics, University of Oxford
- Hannah E. Roberts
- Wellcome Centre for Human Genetics, University of Oxford
- Silvia Salatino
- Wellcome Centre for Human Genetics, University of Oxford
- Helen Lockstone
- Wellcome Centre for Human Genetics, University of Oxford
- Gerton Lunter
- Wellcome Centre for Human Genetics, University of Oxford
- Jenny C. Taylor
- Wellcome Centre for Human Genetics, University of Oxford
- David Buck
- Wellcome Centre for Human Genetics, University of Oxford
- Michael A. Simpson
- Genomics plc
- Peter Donnelly
- Wellcome Centre for Human Genetics, University of Oxford
- DOI
- https://doi.org/10.1038/s41467-019-09637-5
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 9
Abstract
Nanopore sequencing technology generates longer reads than current technologies, but with more errors. Here, the authors develop new analytical tools to improve accuracy and evaluate the potential of nanopore sequencing for clinical human genomics.
