The association of genetic factors with serum calretinin levels in asbestos-related diseases

Zupanc Cita; Franko Alenka; Strbac Danijela; Kovac Viljem; Dolzan Vita; Goricar Katja

doi:10.2478/raon-2023-0061

Radiology and Oncology (Nov 2023)

The association of genetic factors with serum calretinin levels in asbestos-related diseases

Zupanc Cita,
Franko Alenka,
Strbac Danijela,
Kovac Viljem,
Dolzan Vita,
Goricar Katja

Affiliations

Zupanc Cita: Military Medical Unit-Slovenian Army, Ljubljana, Slovenia
Franko Alenka: University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
Strbac Danijela: University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
Kovac Viljem: University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
Dolzan Vita: University of Ljubljana, Faculty of Medicine, Institute of Biochemistry and Molecular Genetics, Pharmacogenetics Laboratory, Ljubljana, Slovenia
Goricar Katja: University of Ljubljana, Faculty of Medicine, Institute of Biochemistry and Molecular Genetics, Pharmacogenetics Laboratory, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2023-0061
Journal volume & issue: Vol. 57, no. 4
pp. 473 – 486

Abstract

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Asbestos exposure is associated with different asbestos-related diseases, including malignant mesothelioma (MM). MM diagnosis is confirmed with immunohistochemical analysis of several markers, including calretinin. Increased circulating calretinin was also observed in MM. The aim of the study was to determine if CALB2 polymorphisms or polymorphisms in genes that can regulate calretinin expression are associated with serum calretinin levels or MM susceptibility.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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