Clinical Evaluation of Enoxaparin Prescription in Mazandaran Heart Center

Abstract

Background and purpose: Drug utilization evaluation (DUE) is one of the most effective methods to assess the correct administration of drugs. Enoxaparin is one of the most commonly used anticoagulant which is widely used as prophylactic or curative treatment. The aim of this study was to evaluate the rational use of enoxaparin in Mazandaran Heart Center. Materials and methods: In a retrospective study, demographic and clinical data of 200 patients who had received enoxaparin in 2017 were collected on the basis of American Hospital Formulary Service (AHFS) drug information, UpToDate, and Medscape guidelines. Results: The mean age of patients was 61.52 ± 13.62 years. The dosing of enoxaparin was according to guidelines in 163 (81.5%) patients and outside the target ranges in 37 (18.5%). Conclusion: In this study, the administration of enoxaparin for therapeutic or prophylactic purposes was not according to guidelines in about one-fifth of the patients and it is necessary to determine the precise dosage.

Keywords

• enoxaparin
• drug utilization evaluation
• prescription pattern