Characterising the phenotypic evolution of circulating tumour cells during treatment

Simon Chang-Hao Tsao; Jing Wang; Yuling Wang; Andreas Behren; Jonathan Cebon; Matt Trau

doi:10.1038/s41467-018-03725-8

Nature Communications (Apr 2018)

Characterising the phenotypic evolution of circulating tumour cells during treatment

Simon Chang-Hao Tsao,
Jing Wang,
Yuling Wang,
Andreas Behren,
Jonathan Cebon,
Matt Trau

Affiliations

Simon Chang-Hao Tsao: Centre for Personalised Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Jing Wang: Centre for Personalised Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Yuling Wang: Centre for Personalised Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Andreas Behren: Olivia Newton-John Cancer Research Institute
Jonathan Cebon: Olivia Newton-John Cancer Research Institute
Matt Trau: Centre for Personalised Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, University of Queensland

DOI: https://doi.org/10.1038/s41467-018-03725-8
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 10

Abstract

Read online

Monitoring the heterogeneity of circulating tumour cells (CTCs) and their phenotypic changes during treatment is a challenge. This study describes and tests a method for detection and quantitative heterogeneity analysis of melanoma CTCs in 10 stage-IV melanoma patients.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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