Diabetes, Metabolic Syndrome and Obesity (May 2022)
A Cross-Sectional Study of Serum Ferritin Levels in Vietnamese Adults with Metabolic Syndrome
Abstract
Thua Nguyen Tran,1 Huu Dang Tran,2 Thanh Tung Tran-Huu,2 Duc Minh Tran,1 Quang Nhat Tran1 1Department of General Internal Medicine and Geriatrics, Hue Central Hospital, Hue City, Vietnam; 2Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue City, VietnamCorrespondence: Thua Nguyen Tran, Department of General Internal Medicine and Geriatrics, Hue Central Hospital, 16 Le Loi Street, Hue City, 530000, Vietnam, Tel +84903597695, Email [email protected]: Metabolic syndrome is one of the most common public health concerns in the 21st century. Several previous studies have shown an association between increased serum ferritin levels and other components of metabolic syndrome and the risk of metabolic syndrome. They conclude that ferritin can be viewed as a predictor of metabolic syndrome risk. This study investigates some main features of metabolic syndrome and the serum ferritin levels in a Vietnamese adult cohort with metabolic syndrome.Methods: A descriptive cross-sectional study was conducted on 207 patients who were treated at the General Internal Medicine-Geriatric Department, Hue Central Hospital, from May 2018 to August 2020. Patients were divided into two groups: the study group (104 patients with metabolic syndrome) and the control group (103 patients without metabolic syndrome and no serum ferritin-mediated disease). The metabolic syndrome was diagnosed by a joint interim statement of the International Diabetes Federation/American Heart Association/National Heart, Lung, and Blood Institute/World Heart Federation/International Atherosclerosis Society/International Association for the Study of Obesity in 2009.Results: Hypertriglyceridemia–hypertension–hyperglycemia (50.9%) is the most common combination of metabolic syndrome components. The mean serum ferritin concentration was 391.62± 181.97ng/mL and 124.55± 63.95ng/mL in the metabolic syndrome and control groups, respectively. In the metabolic syndrome group, increased ferritin concentration accounted for 86.54% for men, the mean serum ferritin concentration was 453.064 ± 161.75ng/mL (increased ferritin concentration accounted for 96.15%) for women; the mean serum ferritin concentration was 330.17 ± 181.71 ng/mL (increased ferritin concentration accounted for 86.54%).Conclusion: The serum ferritin level is significantly increased in Vietnamese patients with metabolic syndrome.Keywords: metabolic syndrome, ferritin, hypertension
