PLoS ONE (Jan 2023)

The effect of body mass index reduction on intraocular pressure in a large prospective cohort of apparently healthy individuals in Israel.

  • Dan Coster,
  • Ariel Rafie,
  • Noam Savion-Gaiger,
  • Rony Rachmiel,
  • Shimon Kurtz,
  • Shlomo Berliner,
  • Itzhak Shapira,
  • David Zeltser,
  • Ori Rogowski,
  • Shani Shenhar-Tsarfaty,
  • Michael Waisbourd

DOI
https://doi.org/10.1371/journal.pone.0285759
Journal volume & issue
Vol. 18, no. 5
p. e0285759

Abstract

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PurposeTo investigate the effect of change in body mass index (BMI) on intraocular pressure (IOP) in a large cohort of apparently healthy volunteers who underwent an annual comprehensive screening examinations.MethodsThis study included individuals who were enrolled in the Tel Aviv Medical Center Inflammation Survey (TAMCIS) and had IOP and BMI measurements at their baseline and follow up visits. Relationships between BMI and IOP and the effect of change in BMI on IOP were investigated.ResultsA total of 7,782 individuals had at least one IOP measurement at their baseline visit, and 2,985 individuals had ≥2 visits recorded. The mean (SD) IOP (right eye) was 14.6 (2.5) mm Hg and mean (SD) BMI was 26.4 (4.1) kg/m2. IOP positively correlated with BMI levels (r = 0.16, pConclusionsBMI loss correlated with reduction in IOP, and this correlation was more pronounced among morbidly obese individuals.