A Review of Primary Immune Deficiency Disorders

Abstract

This scenario-based review of primary immunodeficiency diseases (PIDD) discusses the differential diagnosis, usual presentations, work-up, and treatment of children with the most commonly encountered immune disorders. Newborn screening (NBS) for severe combined immunodeficiency (SCID) is covered, as are later presenting disorders caused by B cell defects and disorders of the innate immune system.

Keywords

• agammaglobulinemia
• b cell deficiency
• hypogammaglobulinemia
• innate immune deficiency
• newborn screening (nbs)
• primary immunodeficiency disorders (pidd)
• t cell deficiency