Nature Communications (Feb 2018)

Heritable DNA methylation marks associated with susceptibility to breast cancer

  • Jihoon E. Joo,
  • James G. Dowty,
  • Roger L. Milne,
  • Ee Ming Wong,
  • Pierre-Antoine Dugué,
  • Dallas English,
  • John L. Hopper,
  • David E. Goldgar,
  • Graham G. Giles,
  • Melissa C. Southey,
  • kConFab

DOI
https://doi.org/10.1038/s41467-018-03058-6
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

Read online

DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.