The Effects of Carotid Endarterectomy Surgery on Cerebral Oxygenation, Randomized Clinical Trial

Abstract

Purpose: The aim of this study is to assess how NIRS values changed with cross-clamp (CC) duration in carotis endarterectomy (CEA) surgeries. Materials and Methods: The study included 30 patients. Before induction of general anesthesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation (SpO2), and regional oxygen saturation(rSO2) values were recorded as right and left sides. The same parameters were recorded before the carotid CC, at the 3rd, 5th, and 10th minutes of the carotid CC, and at the 1st and 5th minutes after the cross-clamp removal postoperatively. Results: When the rSO2 values of the study participants were measured at different times, there was a significant difference (p<0.05) between the right-sided mean rSO2 values of the patients who underwent right-sided surgery (n=11). There was also a significant difference (p<0.05) between the left-sided mean rSO2 values of the patients who underwent left-sided surgery (n=19). Conclusion: We discovered that there was a significant decrease in cerebral oxygen saturation during CC in patients who had CEA surgery under general anesthesia and that cerebral oxygen saturation reached or exceeded the basal value after the CC was opened.

Keywords

• carotid endarterectomy
• cerebral ischemia
• near-infrared spectroscopy