Progress and challenges towards targeted delivery of cancer therapeutics

Daniel Rosenblum; Nitin Joshi; Wei Tao; Jeffrey M. Karp; Dan Peer

doi:10.1038/s41467-018-03705-y

Nature Communications (Apr 2018)

Progress and challenges towards targeted delivery of cancer therapeutics

Daniel Rosenblum,
Nitin Joshi,
Wei Tao,
Jeffrey M. Karp,
Dan Peer

Affiliations

Daniel Rosenblum: Laboratory of Precision NanoMedicine, School of Molecular Cell Biology and Biotechnology, George S. Wise Faculty of Life Sciences, Department of Materials Sciences and Engineering, Iby and Aladar Fleischman Faculty of Engineering; Center for Nanoscience and Nanotechnology, Cancer Biology Research Center, Tel Aviv University
Nitin Joshi: Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
Wei Tao: Center for Nanomedicine and Department of Anesthesiology and, Brigham and Women’s Hospital, Harvard Medical School
Jeffrey M. Karp: Center for Nanomedicine and Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
Dan Peer: Laboratory of Precision NanoMedicine, School of Molecular Cell Biology and Biotechnology, George S. Wise Faculty of Life Sciences, Department of Materials Sciences and Engineering, Iby and Aladar Fleischman Faculty of Engineering; Center for Nanoscience and Nanotechnology, Cancer Biology Research Center, Tel Aviv University

DOI: https://doi.org/10.1038/s41467-018-03705-y
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

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Targeted delivery strategies based on nanocarriers have immense potential to change cancer care but current strategies have been shown only limited translation in the clinic. Here, the authors survey the challenge, progress and opportunities towards targeted delivery of cancer therapeutics.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal