Nature Communications (Nov 2022)
Sharp-wave ripple doublets induce complex dendritic spikes in parvalbumin interneurons in vivo
- Linda Judák,
- Balázs Chiovini,
- Gábor Juhász,
- Dénes Pálfi,
- Zsolt Mezriczky,
- Zoltán Szadai,
- Gergely Katona,
- Benedek Szmola,
- Katalin Ócsai,
- Bernadett Martinecz,
- Anna Mihály,
- Ádám Dénes,
- Bálint Kerekes,
- Áron Szepesi,
- Gergely Szalay,
- István Ulbert,
- Zoltán Mucsi,
- Botond Roska,
- Balázs Rózsa
Affiliations
- Linda Judák
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- Balázs Chiovini
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- Gábor Juhász
- Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter University
- Dénes Pálfi
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- Zsolt Mezriczky
- Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter University
- Zoltán Szadai
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- Gergely Katona
- Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter University
- Benedek Szmola
- Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter University
- Katalin Ócsai
- Two-Photon Measurement Technology Group, The Faculty of Information Technology, Pázmány Péter University
- Bernadett Martinecz
- Momentum Laboratory of Neuroimmunology, Institute of Experimental Medicine
- Anna Mihály
- Faculty of Information Technology and Bionics, Pázmány Péter University
- Ádám Dénes
- Momentum Laboratory of Neuroimmunology, Institute of Experimental Medicine
- Bálint Kerekes
- Faculty of Information Technology and Bionics, Pázmány Péter University
- Áron Szepesi
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- Gergely Szalay
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- István Ulbert
- Faculty of Information Technology and Bionics, Pázmány Péter University
- Zoltán Mucsi
- BrainVisionCenter
- Botond Roska
- BrainVisionCenter
- Balázs Rózsa
- Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine
- DOI
- https://doi.org/10.1038/s41467-022-34520-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
The influence of sharp-wave ripples (SPW-Rs) on dendritic computation remains poorly understood. Here, the authors demonstrate the existence of SPW-R associated, branch-specific, dendritic spikes which serve as a temporal and spatial coincidence detectors during SPW-R-doublets in PV+ interneuron dendrites of awake mice.
