Complexes of 1,8-bis(hydrazidomethylsulfo­nyl)octane and 1,10-bis(hydrazidomethylsulfonyl)decane with copper(II)

Abstract

1,8-bis(hydrazidomethylsulfonyl)octane and 1,10-bis(hydrazidomethylsulfonyl)decane differ by hydrocarbon spacer length, solubility in water, and polymerization tendencies. They and their amides are known to be new antitubercular agents. The substances act as polydentate ligands; in the pH range of 4.5–5.0 and with copper(II), they form cationic mono- and binuclear complexes. Preparatively isolated copper complexes with each of the two compounds have different compositions, which also differ from the composition of complexes in the solution.

Keywords

• 1
• 8-bis(hydrazidomethylsulfonyl)octane
• 10-bis(hydrazidomethylsulfonyl)decane
• copper(ii)
• acid-base properties
• complexation
• ligand denticity
• three-dimensional structure
• elemental analysis
• x-ray crystallography