Comparative study on the clinical effect of minocycline hydrochloride ointment and lodine glycerin as adjuvant therapy for pericoronitis with parulis

Abstract

Objective To compare the clinical effects of minocycline hydrochloride ointment (Periocline) and lodine glycerin as adjuvant therapy for pericoronitis with parulis.Methods 164 college students suffering from pericoronitis with parulis were divided into 2 groups randomly: observation group (82 cases) and control group (82 cases). All cases were treated with incision and drainage of the parulis, and then pericoronal rinsing. What's more, tinidazole and cefradine plus compound borax gargle mouthwash were given to them. 2% Periocline was filled into the periodontal pocket for the observation group (q3d) while 1% lodine glycerin was filled into the periodontal pocket for the control group (qd). Clinical effects of the two groups were observed and compared 3 days later.Results The effective rate of observation group (93.9%) was higher than that of control group (78.0%) with statistically significance (χ2 = 8.546, P = 0.003). No drug adverse reaction occured. Conclusion It shows good effects when Periocline is applied as an adjuvant therapy for pericoronitis with parulis.

Keywords

• The third molar
• Pericoronitis
• Minocycline
• Lodine glycerin
• Release drug