Nanomaterials (May 2023)

Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges

  • Zouhair Ait-Touchente,
  • Nadia Zine,
  • Nicole Jaffrezic-Renault,
  • Abdelhamid Errachid,
  • Noureddine Lebaz,
  • Hatem Fessi,
  • Abdelhamid Elaissari

DOI
https://doi.org/10.3390/nano13101688
Journal volume & issue
Vol. 13, no. 10
p. 1688

Abstract

Read online

Microemulsions are novel drug delivery systems that have garnered significant attention in the pharmaceutical research field. These systems possess several desirable characteristics, such as transparency and thermodynamic stability, which make them suitable for delivering both hydrophilic and hydrophobic drugs. In this comprehensive review, we aim to explore different aspects related to the formulation, characterization, and applications of microemulsions, with a particular emphasis on their potential for cutaneous drug delivery. Microemulsions have shown great promise in overcoming bioavailability concerns and enabling sustained drug delivery. Thus, it is crucial to have a thorough understanding of their formulation and characterization in order to optimize their effectiveness and safety. This review will delve into the different types of microemulsions, their composition, and the factors that affect their stability. Furthermore, the potential of microemulsions as drug delivery systems for skin applications will be discussed. Overall, this review will provide valuable insights into the advantages of microemulsions as drug delivery systems and their potential for improving cutaneous drug delivery.

Keywords