The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells

• Virginia C Rodriguez-Cortez,
• Maria Pilar Navarrete-Meneses,
• Oscar Molina,
• Talia Velasco-Hernandez,
• Jessica Gonzalez,
• Paola Romecin,
• Francisco Gutierrez-Aguera,
• Heleia Roca-Ho,
• Meritxell Vinyoles,
• Eric Kowarz,
• Pedro Marin,
• Sandra Rodriguez-Perales,
• Carlos Gomez-Marin,
• Patricia Perez-Vera,
• Felipe Cortes-Ledesma,
• Anna Bigas,
• Andrea Terron,
• Clara Bueno,
• Pablo Menendez

Affiliations

Virginia C Rodriguez-Cortez

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Maria Pilar Navarrete-Meneses

Laboratorio de Genetica y Cancer, Departamento de Genetica Humana, Instituto Nacional de Pediatria, Ciudad de Mexico

Oscar Molina

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Talia Velasco-Hernandez

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Jessica Gonzalez

Cancer Research Program, Institut Hospital del Mar d'Investigacions Mediques, Hospital del Mar, Barcelona

Paola Romecin

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Francisco Gutierrez-Aguera

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Heleia Roca-Ho

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Meritxell Vinyoles

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona

Eric Kowarz

Institute of Pharmaceutical Biology/DCAL, Goethe-University of Frankfurt, Biocenter, Max-von-Laue-Str. 9, D-60438, Frankfurt/Main

Pedro Marin

Hematology Department. Hospital Clinic de Barcelona

Sandra Rodriguez-Perales

Molecular Cytogenetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Center (CNIO), Madrid

Carlos Gomez-Marin

Topology and DNA breaks Group, Spanish National Cancer Center (CNIO), Madrid

Patricia Perez-Vera

Laboratorio de Genetica y Cancer, Departamento de Genetica Humana, Instituto Nacional de Pediatria, Ciudad de Mexico

Felipe Cortes-Ledesma

Topology and DNA breaks Group, Spanish National Cancer Center (CNIO), Madrid

Anna Bigas

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona, Spain; Cancer Research Program, Institut Hospital del Mar d'Investigacions Mediques, Hospital del Mar, Barcelona, Spain; Centro de Investigacion Biomedica en Red-Oncologia (CIBERONC)

Andrea Terron

European Food and Safety Authority. Parma

Clara Bueno

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona, Spain; Centro de Investigacion Biomedica en Red-Oncologia (CIBERONC)

Pablo Menendez

Josep Carreras Leukemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona. Barcelona, Spain; Centro de Investigacion Biomedica en Red-Oncologia (CIBERONC); Institucio Catalana de Recerca i Estudis Avancats (ICREA), Barcelona