JACS Au (Sep 2023)
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy
- Yong Sun,
- Hongbo Zheng,
- Lilin Qian,
- Yue Liu,
- Deyu Zhu,
- Zejun Xu,
- Wenqiang Chang,
- Jianwei Xu,
- Lei Wang,
- Bin Sun,
- Lichuan Gu,
- Huiqing Yuan,
- Hongxiang Lou
Affiliations
- Yong Sun
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Hongbo Zheng
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Lilin Qian
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Yue Liu
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Deyu Zhu
- Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China
- Zejun Xu
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Wenqiang Chang
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- Jianwei Xu
- Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China
- Lei Wang
- Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China
- Bin Sun
- National Glycoengineering Research Center, Shandong University, Jinan, China
- Lichuan Gu
- State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China
- Huiqing Yuan
- Key Laboratory of Experimental Teratology of the Ministry of Education, Institute of Medical Sciences, The Second Hospital of Shandong University, Jinan, China
- Hongxiang Lou
- Department of Natural Products Chemistry, Key Laboratory of Natural Products & Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
- DOI
- https://doi.org/10.1021/jacsau.3c00228
- Journal volume & issue
-
Vol. 3,
no. 10
pp. 2749 – 2762
Abstract
No abstracts available.
