Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report

Abdullah Ramadhan; Anita Troung; Elaine Yacyshyn; Robert Gniadecki

doi:10.1177/2050313X251350376

SAGE Open Medical Case Reports (Jun 2025)

Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report

Abdullah Ramadhan,
Anita Troung,
Elaine Yacyshyn,
Robert Gniadecki

Affiliations

Abdullah Ramadhan: Department of Dermatology, University of Alberta, Edmonton, AB, Canada
Anita Troung: Department of Dermatology, University of Alberta, Edmonton, AB, Canada
Elaine Yacyshyn: Department of Dermatology, University of Alberta, Edmonton, AB, Canada
Robert Gniadecki: Department of Dermatology, University of Alberta, Edmonton, AB, Canada

DOI: https://doi.org/10.1177/2050313X251350376
Journal volume & issue: Vol. 13

Abstract

Read online

A 61-year-old female with systemic lupus erythematosus presented with refractory discoid lupus. Despite treatment with numerous immunosuppressive therapies, including prednisone, hydroxychloroquine and mycophenolate mofetil, her cutaneous lupus remained active and significantly impacted her quality of life. Introduction of anifrolumab led to remarkable improvement, highlighting its potential for refractory discoid lupus erythematosus.

Published in SAGE Open Medical Case Reports

ISSN: 2050-313X (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Medicine (General)
Website: https://journals.sagepub.com/home/sco

About the journal