BMC Surgery (Nov 2023)

Analysis of serum calcium change trajectories and prognostic factors in patients with acute type A aortic dissection

  • Jian-Long Lin,
  • Sai-Lan Li,
  • Yan-Chun Peng,
  • Liang-Wan Chen,
  • Yan-Juan Lin

DOI
https://doi.org/10.1186/s12893-023-02249-3
Journal volume & issue
Vol. 23, no. 1
pp. 1 – 11

Abstract

Read online

Abstract Objectives This study aimed to analyze the correlation between serum calcium changes and short-term prognosis of patients with acute type A aortic dissection. Methods Patients who underwent acute type A aortic dissection surgery at Fujian Heart Medical Center between June 2019 and June 2021 were retrospectively analyzed. Results A total of 383 patients were enrolled. According to the changing track of serum calcium in patients after acute type A aortic dissection, three potential category tracks were determined: high-level (n = 85), medium-level (n = 259), and continuous low-level groups (n = 39). Using the medium-level group as the control, regression analysis showed that poor prognosis risk was increased in the group with continuous low serum calcium (odds ratio = 2.454, P 48 h (odds ratio = 3.595, P < 0.05). Age (odds ratio = 1.063, P < 0.001), body mass index (odds ratio = 1.138, P < 0.05), hypertension (odds ratio = 3.697, P < 0.05), and the highest lactic acid within 72 h after surgery(odds ratio = 1.093, P < 0.05) were independent risk factors for poor prognosis after aortic dissection. Conclusion Continuous low serum calcium was an independent predictor of poor prognosis in patients with acute type A aortic dissection.

Keywords