The Relationship of Blood Parameters with the Severity of Carbon Monoxide Poisoning

Abstract

Introduction: Carbon monoxide (CO) poisoning is one of the most common poisonings worldwide. Many studies have investigated the relationship between predictive parameters and CO poisoning severity. We aimed to investigate the relationship between blood parameter values with poor outcome in CO poisoning, and CO values measured in blood. Methods: This is a retrospective study. Patients who had CO levels ≥ %10 in their blood gas were included in the study. Patients were divided into 2 groups as those who required hyperbaric oxygen and those who do not. Demographic data such as age, gender of the patients, as well as CO levels in the blood gases of the patients, hemoglobin, leukocyte, neutrophil, platelet counts of the blood count, and MPV and PDW values were recorded. Also, creatinine, troponin, CRP, ALT values were recorded as well. Results: The study was conducted with 110 patients. The mean age of the patients was 46.80±18.18 years. When the parameters were examined, the median WBC count of patients with patients who required HBO therapy was 8.73[7.54-11.83], and the median WBC count of patients who did not require HBO therapy was 8.01[6.96-9.72] (p=0.038). The median lymphocyte count of patients who required HBO therapy was determined as 2.73[1.85-3.36], and this value was found to be higher than patients who did not require HBO therapy (p=0.026). Conclusion: WBC and lymphocyte counts are higher in CO poisoning patients who required hyperbaric oxygen therapy. But these two values were not found to be independent risk factors in predicting hyperbaric oxygen therapy.

Keywords

• poisoning
• carbon monoxide
• oxygen
• lymphocyte
• leukocytes
• zehirlenme
• karbonmonoksit
• oksijen
• lenfosit
• lökosit