Case Reports in Oncology (Jul 2017)

Successful Yttrium-90 Microsphere Radioembolization for Hepatic Metastases of Prostate Cancer

  • Alexander C. Bunck,
  • Daniel Pinto dos Santos,
  • De-Hua Chang,
  • Marcel Reiser,
  • David Pfister,
  • Anne Bunck,
  • Alexander Drzezga,
  • David Maintz,
  • Matthias Schmidt

DOI
https://doi.org/10.1159/000478004
Journal volume & issue
Vol. 10, no. 2
pp. 627 – 633

Abstract

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Prostate cancer is the most common solid tumor malignancy worldwide with an estimated 180,000 new cases of prostate cancer and 26,000 deaths in the USA in 2016. Although significant advances in the treatment of prostate cancer have recently been made, the treatment of metastatic disease remains a challenge. With visceral metastases marking more advanced tumor stages, liver involvement is associated with the worst prognosis. So far, no locoregional treatment regimens for the management of liver metastases of prostatic cancer exist. Herein, we report for the first time a successful treatment of hepatic metastases of prostatic cancer using radioembolization with selective intra-arterial administration of Yttrium-90 resin microspheres.

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