Gene-environment interaction explains a part of missing heritability in human body mass index

Hae-Un Jung; Dong Jun Kim; Eun Ju Baek; Ju Yeon Chung; Tae Woong Ha; Han-Kyul. Kim; Ji-One Kang; Ji Eun Lim; Bermseok Oh

doi:10.1038/s42003-023-04679-4

Communications Biology (Mar 2023)

Gene-environment interaction explains a part of missing heritability in human body mass index

Hae-Un Jung,
Dong Jun Kim,
Eun Ju Baek,
Ju Yeon Chung,
Tae Woong Ha,
Han-Kyul. Kim,
Ji-One Kang,
Ji Eun Lim,
Bermseok Oh

Affiliations

Hae-Un Jung: Department of Biomedical Science, Graduate School, Kyung Hee University
Dong Jun Kim: Department of Biomedical Science, Graduate School, Kyung Hee University
Eun Ju Baek: Department of Biomedical Science, Graduate School, Kyung Hee University
Ju Yeon Chung: Department of Biomedical Science, Graduate School, Kyung Hee University
Tae Woong Ha: Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University
Han-Kyul. Kim: Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University
Ji-One Kang: Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University
Ji Eun Lim: Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University
Bermseok Oh: Department of Biomedical Science, Graduate School, Kyung Hee University

DOI: https://doi.org/10.1038/s42003-023-04679-4
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 11

Abstract

Read online

A study on the effects of gene-environment interactions on body mass index (BMI) in the UK Biobank cohort finds BMI genetic loci that interact with lifestyle traits such as physical activity, smoking, and alcohol consumption.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal