Детские инфекции (Москва) (Jun 2016)

Interferon Status and Choice of Interferons Inducers in Frequently Ill Children

  • M. S. Savenkovа,
  • O. V. Karashtinа,
  • M. B. Shabat,
  • G. N. Kraseva,
  • N. A. Abramova,
  • T. E. Kraseva

DOI
https://doi.org/10.22627/2072-8107-2016-15-2-45-51
Journal volume & issue
Vol. 15, no. 2
pp. 45 – 51

Abstract

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Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has only failure of interferon system, and 34% of FIC has violations of humoral immunity in combination with interferon system failure. At the same time, all children suffering occasionally was detected only insufficiency of interferon system and humoral immunity was within normal limits. Based on the study of individual sensitivity of white blood cells justifies the choice of interferons inducers.

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