Efficacy of On-Site Evaluation in EBUS-Guided Transbronchial Needle Aspiration Versus Cell Block

Abstract

Objective: To determine Rapid onsite evaluation (ROSE) effectiveness, sensitivity and specificity during Endoscopic ultrasound guided Transbronchial needle aspiration (EBUS TBNA) and compare it with cell blocks prepared during same process. Study Design: Diagnostic Accuracy Study. Place and Duration of Study: Pathology department of Akhtar Saeed Medical College and Watim Medical and Dental College, from June 15, 2023, to June 15, 2024. Materials and Methods: After getting approval from ERB, a written informed consent was taken from all the enrolled 110 patients who went through EBUS-TBNA in Farooq Hospital and Watim general Hospital depending upon inclusion and exclusion criteria. The age limit was more than 20 years and less than 65 years, including both genders. ROSE, EBUS TBNA and cell blocks of the patients diagnosed on CT scan with mediastinal or hilar masses were analyzed. Results: Diagnostic parameters were calculated using ROC Curve analysis in SPSS version 23. Sensitivity of EBUS-TBNA with ROSE was discovered to be 95%, specificity was 60%, positive predictive value and negative predictive value were calculated to be 98.1% and 96 % respectively. Procedure's diagnostic accuracy of process with ROSE was 98%. Conclusion: This study concludes that ROSE performed during EBUS TBNA has high sensitivity, moderately effective specificity and high concordance rate with cell block examination. It serves as a valuable adjunct to limit procedure time, enrich sample collection and benefit patient's well-being.

Keywords

• cell block
• ebus tbna
• mediastinal
• rose