OncoImmunology (Dec 2023)
Histamine antagonists promote cancer immunosurveillance
Abstract
ABSTRACTRecently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype and to increase their anticancer activity in the context of immunochemotherapy.
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