Study on synthesis of ethyl 3-ethyl-5-pyrazolecarbonylate(3-乙基-5-吡唑酸乙酯的合成研究)

TANCheng-xia(谭成侠); SHENDe-long(沈德隆); WENGJian-quan(翁建全); FANDe-fang(樊德方)

doi:zjup/1008-9497.2005.32.2.204-206

Zhejiang Daxue xuebao. Lixue ban (Mar 2005)

Study on synthesis of ethyl 3-ethyl-5-pyrazolecarbonylate(3-乙基-5-吡唑酸乙酯的合成研究)

TANCheng-xia(谭成侠),
SHENDe-long(沈德隆),
WENGJian-quan(翁建全),
FANDe-fang(樊德方)

Affiliations

TANCheng-xia(谭成侠): 1.College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China( 1.浙江大学农业与生物技术学院，浙江杭州 310029)
SHENDe-long(沈德隆): 2.Zhejiang University of Technology, Hangzhou 310014, China( 2.浙江工业大学，浙江杭州 310014)
WENGJian-quan(翁建全): 2.Zhejiang University of Technology, Hangzhou 310014, China( 2.浙江工业大学，浙江杭州 310014)
FANDe-fang(樊德方): 1.College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China( 1.浙江大学农业与生物技术学院，浙江杭州 310029)

DOI
Journal volume & issue: Vol. 32, no. 2
pp. 204 – 206

Abstract

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在合成中间体丙酰丙酮酸乙酯中，对反应温度和反应溶剂进行了优化试验，发现用乙醚作溶剂在5 ℃以下时，反应收率和中间体质量分数分别达到90% 和95% 以上.制备3-乙基-5吡唑酸乙酯中，对反应温度和丙酰丙酮酸乙醋与水合肼摩尔比进行了优化试验，发现在0 ℃以下，摩尔比在1：1.2以上时，目标产物的质量分数和收率达到94% 和87% 以上.

Published in Zhejiang Daxue xuebao. Lixue ban

ISSN: 1008-9497 (Print)
Publisher: Zhejiang University Press
Country of publisher: China
LCC subjects: Science: Mathematics: Instruments and machines: Electronic computers. Computer science; Science: Physics
Website: https://www.zjujournals.com/sci/EN/1008-9497/home.shtml

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