Case Reports in Obstetrics and Gynecology (Jan 2014)

An Unusual Case of Fulminant Type 1 Diabetes during the Second Trimester of Pregnancy

  • Tomohiro Okuda,
  • Sadao Yamashita,
  • Yoshio Ogino,
  • Hisashi Kataoka,
  • Jo Kitawaki

DOI
https://doi.org/10.1155/2014/968547
Journal volume & issue
Vol. 2014

Abstract

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Fulminant type 1 diabetes is a new subtype of rapid-onset type 1 diabetes, with pancreatic exocrine dysfunction, that usually develops during the third trimester of pregnancy. We describe a patient with fulminant type 1 diabetes onset during her second trimester, resulting in premature delivery. The 34-year-old woman, without any known risk factors for diabetes mellitus, experienced a sudden stillbirth at 24-weeks gestation. Her blood glucose level was 950 mg/dL and she was positive for urine ketone bodies. The condition met all the diagnostic criteria for fulminant type 1 diabetes, and was diagnosed as such. Although this disease is rare, its progression is rapid, and its clinical course is severe and occasionally leads to death; therefore, a full knowledge of the disease is important to facilitate an accurate diagnosis.