Relapsed multiple myeloma manifesting as extramedullary plasmacytoma of the breast: Imaging findings

Misugi Urano, MD; Fatmaelzahraa Abdelfattah Denewar, MD; Ryo Okabe, MD; Hirokazu Komatsu, MD; Yumi Wanifuchi-Endo, MD; Tatsuya Toyama, MD; Yuta Shibamoto, MD

Radiology Case Reports (May 2019)

Relapsed multiple myeloma manifesting as extramedullary plasmacytoma of the breast: Imaging findings

Misugi Urano, MD,
Fatmaelzahraa Abdelfattah Denewar, MD,
Ryo Okabe, MD,
Hirokazu Komatsu, MD,
Yumi Wanifuchi-Endo, MD,
Tatsuya Toyama, MD,
Yuta Shibamoto, MD

Affiliations

Misugi Urano, MD: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Mizuho-ku, Nagoya, Japan; Corresponding author.
Fatmaelzahraa Abdelfattah Denewar, MD: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Mizuho-ku, Nagoya, Japan
Ryo Okabe, MD: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Mizuho-ku, Nagoya, Japan
Hirokazu Komatsu, MD: Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Division of Chemotherapy, Nagoya City University Hospital, Japan
Yumi Wanifuchi-Endo, MD: Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Tatsuya Toyama, MD: Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Yuta Shibamoto, MD: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Mizuho-ku, Nagoya, Japan

Journal volume & issue: Vol. 14, no. 5
pp. 584 – 587

Abstract

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Extramedullary plasmacytoma of the breast (EPB), a manifestation of multiple myeloma (MM), is very rare. It is important to recognize the imaging findings of EPB because it may be the first manifestation of relapsed MM. An 85-year-old woman presented with a lump in her right breast 4 years after the complete remission of MM. She underwent mammography and ultrasonography, which showed an oval circumscribed mass and an irregular circumscribed heterogeneous solid mass, respectively. Following ultrasound-guided vacuum-assisted breast biopsy, this lesion was confirmed to be EPB. Whole-body computed tomography showed multiple new osteolytic lesions and other multiple extramedullary lesions in addition to EPB in the right breast. The final diagnosis was relapsed MM with multiple extramedullary plasmacytoma. Keywords: Plasmacytoma, Breast, Multiple Myeloma, Ultrasonography, Mammography

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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