RETRACTED: Efficacy and safety of medicines: the value and opportunities of clinical pharmacology

Abstract

RETRACTED ARTICLEBrief description of the opportunities and benefits of applying the methodology of clinical pharmacology and personalized medicine, pharmacokinetics, and pharmacodynamics of medicines, as well as the possibilities of evaluation of metabolic biotransformation and drug interactions to improve the efficacy, safety, therapeutic and pharmacodynamic effects of medicines, is given. These features and techniques should be extensively used for expert evaluation of efficacy and safety of drugs. The introduction of modern methods of diagnostics and treatment in clinical practice will require building a system that could be implemented in the Centres of personalized medicine.

Keywords

• efficacy
• safety
• pharmacokinetics
• interaction
• pharmacodynamics
• pharmacogenetics
• medicines
• эффективность
• безопасность
• фармакокинетика
• взаимодействие
• фармакодинамика
• фармакогенетика
• лекарственные препараты