Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B‐cell acute lymphoblastic leukemia

Abstract

Key Clinical Message Patients with B‐lineage acute lymphoblastic leukemia treated with pegasparaginase‐containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

Keywords

• ALL
• CSF xanthochromia
• hepatotoxicity
• pegasparaginase