Interleukin-6 (IL-6), Interleukin-8 (IL-8), and Tumor Necrosis FactorAlpha (TNF-a): Their Role in the Development and Metastasis of Tumor Cells

Abstract

ABSTRACT: Cancer is a disease caused by uncontrolled and excessive cell division. The death caused by cancer is largely due to the cancer cell metastasis process. Cancer metastasis process is a consequence of molecules signaling pathways and interactions amongst cells in the body. Molecules involved and attributable to cancer metastasis are IL-6, IL-8, and TNF-α. This article aimed to describe the roles of IL-6, IL-8, and TNF-α in the process of various cancer cases.

Keywords

• cancer, il-6, il-8, tnf-alpha, metastasis