Clinical profile of COVID-19 patients and association between morbidities and mortality due to COVID-19 at a tertiary care center

Abstract

Background: The globe has faced a number of challenges in recent years from viral epidemics brought on by newly developing zoonotic diseases, particularly the coronavirus family of viruses. Patients with COVID-19 disease are more likely to experience a more severe course and progression of the disease if they also have comorbid conditions such as hypertension or diabetes mellitus. Hence, the present study was carried out to study the clinical characteristics of COVID-19 patients and the association between COVID-19-related morbidities and mortality in a tertiary care center. Objectives: The objective of this study was to study the clinical profile of COVID-19 patients and the relationship between COVID-19-related morbidities and death at a tertiary care facility. Methodology: The present study was a cross-sectional study which was carried out in the tertiary care hospital of Central India from March 2020 to August 2021 on 11,201 patients. Results: Among the 11,201 study subjects, 6755 (60.31%) were males and 4446 (39.69%) were females. The majority of the study subjects, 2428 (21.68%), were between the age group of 51–60 years. Cough was the major presenting complaint found in 5243 (46.81%) study subjects. Hypertension was the main morbid condition in 2249 (20.08%) study subjects. Among the 11,201 admitted patients, 8763 (78.23%) were discharged, and in 2438 (21.77%) study subjects, the outcome was death. Conclusions: Since morbid conditions such as diabetes and hypertension were more prevalent and it affects more in COVID-19 disease mortality.

Keywords

• comorbidity
• covid-19
• mortality
• outbreak
• pandemic
• quarantine
• zoonotic diseases