Control of adverse drug reactions in HIV/AIDS antiretroviral treatment with interchangeable medicines

Abstract

Review on assessment data of ADR, which must be monitored during antiretroviral therapy in patients with HIV/AIDS are presented. Questions of drug safety acquire particular importance in conducting pharmacotherapy of the most socially significant diseases, which include HIV/AIDS. Currently there is a sufficient number of generic drugs for antiretroviral therapy, which form the basis for affordable health care. The correlation of efficacy and safety of generic drugs, their interchangeability assessment require constant study of the antiretroviral drugs influence on various systems of the body. Particular attention should be given to the cardiovascular disorders and hepatotoxicity.

Keywords

• нежелательная лекарственная реакция
• антиретровирусная терапия
• воспроизведенные лекарственные препараты
• взаимозаменяемость
• adverse drug reaction (adr)
• antiretroviral therapy (arvt)
• generic drugs
• interchangeability