Nature Communications (Sep 2022)

Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells

  • Juraj Adamik,
  • Paul V. Munson,
  • Felix J. Hartmann,
  • Alexis J. Combes,
  • Philippe Pierre,
  • Matthew F. Krummel,
  • Sean C. Bendall,
  • Rafael J. Argüello,
  • Lisa H. Butterfield

DOI
https://doi.org/10.1038/s41467-022-32849-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 19

Abstract

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Assessing metabolic activity within single cells rather than at a population level has a number of advantages. Here, the authors use a flow and mass cytometry based approach that assess the metabolic differences between populations of human immune stimulatory and tolerogenic dendritic cells.