Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives

• Mingming Zhang,
• Allan M. Prior,
• Marcus M. Maddox,
• Wan-Jou Shen,
• Kirk E. Hevener,
• David F. Bruhn,
• Robin B. Lee,
• Aman P. Singh,
• Justin Reinicke,
• Charles J. Simmons,
• Julian G. Hurdle,
• Richard E. Lee,
• Dianqing Sun

Affiliations

Mingming Zhang

Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, Hilo, Hawaii, United States

Allan M. Prior

Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, Hilo, Hawaii, United States

Marcus M. Maddox

Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Wan-Jou Shen

Center for Infectious and Inflammatory Diseases, Texas A&M Health Science Center, Houston, Texas, United States

Kirk E. Hevener

Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States

David F. Bruhn

Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Robin B. Lee

Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Aman P. Singh

Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Justin Reinicke

Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, Hilo, Hawaii, United States

Charles J. Simmons

Department of Chemistry, University of Hawai’i at Hilo, Hilo, Hawaii, United States

Julian G. Hurdle

Center for Infectious and Inflammatory Diseases, Texas A&M Health Science Center, Houston, Texas, United States

Richard E. Lee

Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Dianqing Sun

Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, Hilo, Hawaii, United States