Rare case of blastemal predominant adult Wilms′ tumor with skeletal metastasis case report and brief review of literature

Abstract

Wilms′ tumor (nephroblastoma) is extremely rare in adults, skeletal metastasis being still rarer. The clinical course of adult Wilms′ tumor is very aggressive. The present case is a rare blastemal predominant adult Wilms′ tumor presenting with skeletal metastasis. We report a case of 19-year-old female presented with severe low backache and colicky left loin pain of 3 months and progressive weakness of 15 days duration. Magnetic resonance image (MRI) of lumbosacral spine was reported as spinal metastasis with right renal mass. The patient underwent right radical nephrectomy and the tumor was histopathologically confirmed as adult Wilms′ tumor. In case of adult Wilms′ tumor, distant metastasis may be the first presentation and this possibility should be considered when an adult patient presents with flank pain and a renal mass.

Keywords

• Adult Wilms′ tumor
• renal tumor
• skeletal metastasis