Animals (Aug 2021)

Stage 1-Biomarkers of Kidney Injury in Dogs Undergoing Constant Rate Infusion of Hydroxyethyl Starch 130/0.4

  • Barbara Bruno,
  • Roberta Troìa,
  • Francesco Dondi,
  • Cristiana Maurella,
  • Paola Gianella,
  • Ilaria Lippi,
  • Alberto Tarducci,
  • Antonio Borrelli

DOI
https://doi.org/10.3390/ani11092555
Journal volume & issue
Vol. 11, no. 9
p. 2555

Abstract

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In veterinary medicine, investigations relating the effects of hydroxyethyl starch (HES) on renal function report contrasting results. This study aimed to assess the changes in the selected biomarkers of kidney injury in dogs after the administration of HES 130/0.4 as a constant rate infusion (CRI) for 24 h. Ten adult client-owned dogs with hypoalbuminemia (albumin p = 0.04) was noticed between the baseline and T48. In this study sample of hypoalbuminemic dogs, HES 130/0.4 at the dose and rate of infusion applied did not cause any significant changes in the investigated biomarkers of kidney injury.

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