Predictive Models of Muscle Strength in Older People with Type 2 Diabetes Mellitus

Abstract

Mateus Medeiros Leite,1 Ivo Vieira de Sousa Neto,2 Maurílio Tiradentes Dutra,3 Silvana Schwerz Funghetto,1 Alessandro de Oliveira Silva,4 Izabel Cristina Rodrigues da Silva,1 Luciano Ramos de Lima,5 Marina Morato Stival1 1Graduate Program in Health Sciences and Technologies, University of Brasilia, Faculty of Ceilândia, Brasilia, Brazil; 2School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), São Paulo, Brazil; 3Federal Institute of Education, Science and Technology of Brasília, Brasilia, Brazil; 4Physical Education Department, University Center of Brasilia - UniCEUB, Brasilia, Brazil; 5Nursing Course, University of Brasilia, Faculty of Ceilândia, Brasilia, BrazilCorrespondence: Mateus Medeiros Leite, University of Brasilia, Graduate Program in Health Sciences and Technologies, Faculty of Ceilândia, Brasilia, Brasilia, Federal District, Brazil – Campus Universitario, s/n, Centro Metropolitano, Brasília, 72220-275, Brazil, Tel + 55 61 998541966, Email [email protected]: To propose predictive models for absolute muscle strength (AMS) of elderly people with type 2 Diabetes Mellitus (DM2) in primary health care.Patients and Methods: The cross-sectional study was conducted with 138 elderly diabetics. The AMS was measured by a JAMAR® hydraulic handgrip dynamometer, determined by the sum of both hands. The following indices were evaluated: waist-to-height ratio (WHtR), body mass index (BMI), Lipid Accumulation Product (LAP), Triglyceride/High Density Lipoprotein (TG/HDL) ratio and platelet/lymphocyte ratio (PLR). Multiple linear regression was used in the statistical analysis.Results: The final regression model indicated 66.4% (R²=0.66) of the variation in AMS. WHtR decreased AMS by 41.1% (β = − 0.19; t = − 3.70; p < 0.001), while PLR by 11.3% (β = − 0.12; t = − 2.36; p = 0.020). Male sex increased AMS by 10.6% (β = 0.32; t = 4.16; p < 0.001), and lean mass (LM) by 0.89% (β = 0.46; t = 6.03; p < 0.001).Conclusion: WHtR and PLR predicted a decrease, while male sex and LM predicted an increase in AMS. It is suggested that these markers be used as screening measures for variation in AMS in older adults with DM2. These results have relevant practical application in primary health care since the markers are easy to use.Keywords: handgrip strength, obesity, diabetes mellitus, inflammation, primary health care

Keywords

• handgrip strength. obesity. diabetes mellitus. inflammation. primary health care.