Myocardial electrical activity according to daily ECG monitoring in patients with heart failure with preserved ejection fraction and asymptomatic diastolic dysfunction

Abstract

Aim. To evaluate changes in the electrical activity of the myocardium according to the daily monitoring of ECG and explore their relationship with structural and functional condition of the heart in patients with heart failure with preserved ejection fraction and asymptomatic diastolic dysfunction after myocardial infarction on the background of hypertension. Methods and results. For evaluating changes in the electrical activity of the myocardium and study their relationship with those structural and functional condition of the heart in 36 patients with preserved left ventricular ejection fraction after myocardial infarction with hypertension the next methods were used: ECG monitoring, echocardiography and serum NTproBNP level detection. Increased number of the ventricular beats (by 56.9%; p<0.05) and duration of ischemic episodes per day (17%; p<0.05), reducing time and spectral parameters of sinus rhythm variability – SDNN (at 41.3%; p<0.05), SDANN (by 38.9%; p<0.05), pNN50 (43.8%; p<0.05), LF (at 36.4%; p<0.05), VLF (at 17.5%; p<0.05) and LF/HF (at 54.2%; p<0.05) were detected in patients with heart failure with preserved left ventricular ejection fraction compared with patients with asymptomatic diastolic dysfunction. Conclusion. Increased number of ventricular beats, duration of ischemia episodes per day and significant reduction in variability of sinus rhythm were found in patients with heart failure with preserved ejection fraction after myocardial infarction on the background of hypertension.

Keywords

• Heart Failure
• Leftventricular Dysfunction
• Myocardial Infarct
• Hypertension