Traffic-related air pollution is a risk factor in the development of chronic obstructive pulmonary disease

Jinzhen Zheng; Jinzhen Zheng; Sha Liu; Sha Liu; Jieqi Peng; Jieqi Peng; Huanhuan Peng; Huanhuan Peng; Zihui Wang; Zhishan Deng; Chenglong Li; Naijian Li; Longhui Tang; Longhui Tang; Jianwu Xu; Jingwen Li; Bing Li; Bing Li; Yumin Zhou; Yumin Zhou; Pixin Ran; Pixin Ran

doi:10.3389/fpubh.2022.1036192

Frontiers in Public Health (Dec 2022)

Traffic-related air pollution is a risk factor in the development of chronic obstructive pulmonary disease

Jinzhen Zheng,
Jinzhen Zheng,
Sha Liu,
Sha Liu,
Jieqi Peng,
Jieqi Peng,
Huanhuan Peng,
Huanhuan Peng,
Zihui Wang,
Zhishan Deng,
Chenglong Li,
Naijian Li,
Longhui Tang,
Longhui Tang,
Jianwu Xu,
Jingwen Li,
Bing Li,
Bing Li,
Yumin Zhou,
Yumin Zhou,
Pixin Ran,
Pixin Ran

Affiliations

Jinzhen Zheng: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Jinzhen Zheng: Department of Pulmonary and Critical Care Medicine, Shantou Central Hospital, Shantou, Guangdong, China
Sha Liu: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Sha Liu: The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China
Jieqi Peng: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Jieqi Peng: Guangzhou Laboratory, Bio Island, Guangzhou, Guangdong, China
Huanhuan Peng: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Huanhuan Peng: Department of Pulmonary and Critical Care Medicine, The Fourth People's Hospital of Chenzhou, Chenzhou, Hunan, China
Zihui Wang: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Zhishan Deng: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Chenglong Li: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Naijian Li: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Longhui Tang: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Longhui Tang: Department of Pulmonary and Critical Care Medicine, Chenzhou Third People's Hospital, Chenzhou, Hunan, China
Jianwu Xu: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Jingwen Li: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Bing Li: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Bing Li: College of Life Sciences, Guangzhou Medical University, Guangzhou, Guangdong, China
Yumin Zhou: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Yumin Zhou: Guangzhou Laboratory, Bio Island, Guangzhou, Guangdong, China
Pixin Ran: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, The Guangzhou Institute of Respiratory Health, and The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China
Pixin Ran: Guangzhou Laboratory, Bio Island, Guangzhou, Guangdong, China

DOI: https://doi.org/10.3389/fpubh.2022.1036192
Journal volume & issue: Vol. 10

Abstract

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BackgroundOutdoor traffic-related air pollution has negative effects on respiratory health. In this study, we aimed to explore the effect of outdoor traffic-related air pollution on chronic obstructive pulmonary disease (COPD) in Guangzhou.MethodsWe enrolled 1,460 residents aged 40 years or older between 21 January 2014 and 31 January 2018. We administered questionnaires and spirometry tests. The distance of participants' residences or locations of outdoor activities from busy roads (as indicators of outdoor traffic-related air pollution), indoor air pollution, and smoking history were queried in the questionnaires.ResultsOf the 1,460 residents with valid survey and test results, 292 were diagnosed with COPD, with a detection rate of 20%. Participants who lived and did their outdoor activities near busy roads had a higher detection rate of COPD. Among residents living at distances of <50 meters, 50–199 meters, and more than 200 meters from busy roads, the detection rates were 20.6, 21.2, and 14.8%, respectively; the rates for outdoor activities at these distances were 23.8, 24.5, and 13.7%, respectively (p < 0.05). After adjusting for sex, age, smoking status, family history, and smoking index, the distance of outdoor activities from busy roads was an independent risk factor for COPD. Participants whose outdoor activities were conducted <50 meters and 50–199 meters of main roads had odds ratios of 1.54 (95% confidence interval 1.01–2.36) and 1.84 (95% interval 1.23–2.76) for the risk of COPD in comparison with a distance of more than 200 meters from busy roads.ConclusionsResidents of Guangzhou whose outdoor activities were close to busy roads had a high risk of COPD. Traffic-related air pollution presents a risk to human health and a risk of COPD.

Published in Frontiers in Public Health

ISSN: 2296-2565 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Public aspects of medicine
Website: https://www.frontiersin.org/journals/public-health

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