Phytochemicals and Their Usefulness in the Maintenance of Health
Elda Victoria Rodríguez-Negrete,
Ángel Morales-González,
Eduardo Osiris Madrigal-Santillán,
Karina Sánchez-Reyes,
Isela Álvarez-González,
Eduardo Madrigal-Bujaidar,
Carmen Valadez-Vega,
German Chamorro-Cevallos,
Luis Fernando Garcia-Melo,
José A. Morales-González
Affiliations
Elda Victoria Rodríguez-Negrete
Servicio de Gastroenterología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 06720, Mexico
Ángel Morales-González
Escuela Superior de Cómputo, Instituto Politécnico Nacional, Unidad Profesional ”A. López Mateos”, Ciudad de México 07738, Mexico
Eduardo Osiris Madrigal-Santillán
Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C.P. 11340, Mexico
Karina Sánchez-Reyes
Servicio de Cirugía General, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 06720, Mexico
Isela Álvarez-González
Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Zacatenco, Gustavo A. Madero, Mexico City 07738, Mexico
Eduardo Madrigal-Bujaidar
Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Zacatenco, Gustavo A. Madero, Mexico City 07738, Mexico
Carmen Valadez-Vega
Área Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, San Agustín Tlaxiaca 42080, Mexico
German Chamorro-Cevallos
Laboratorio de Toxicología Preclínica, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City C.P. 07738, Mexico
Luis Fernando Garcia-Melo
Laboratorio de Nanotecnología e Ingeniería Molecular, Área Electroquímica, Departamento de Química, CBI, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City 09340, Mexico
José A. Morales-González
Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C.P. 11340, Mexico
Inflammation is the immune system’s first biological response to infection, injury, or irritation. Evidence suggests that the anti-inflammatory effect is mediated by the regulation of various inflammatory cytokines, such as nitric oxide, interleukins, tumor necrosis factor alpha-α, interferon gamma-γ, as well as the non-cytokine mediator, prostaglandin E2. Currently, the mechanism of action and clinical usefulness of phytochemicals is known; their action on the activity of cytokines, free radicals, and oxidative stress. The latter are of great relevance in the development of diseases, such that the evidence collected demonstrates the beneficial effects of phytochemicals in maintaining health. Epidemiological evidence indicates that regular consumption of fruits and vegetables is related to a low risk of developing cancer and other chronic diseases.